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Posted by j0hn on August 26th, 2007 — in Soma Top News
FRAZER, Pa. -
Cephalon Inc. Thursday signed an agreement to buy the extended release muscle relaxant Amrix from ECR Pharmaceuticals, according to the drug’s licensor and maker Eurand N.V.
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Eurand will now work with Cephalon (nasdaq: CEPH - news - people ) to support the commercialization of the drug in the United States. Eurand will receive royalty payments from Cephalon on the sales.
Shares of Cephalon rose 15 cents to $71.39
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Posted by j0hn on August 19th, 2007 — in Soma Top News
AMSTERDAM (Thomson Financial) - Akzo Nobel NV’s Organon said its neuromuscular blocking agent Eslax, a muscle relaxant, has been given approval for use in Japan by local regulatory authorities.
The company said the approval adds to the drug’s list of approved countries, including the United States, Canada and various European countries.
Organon said its Japanese affiliate, Nippon Organon, will introduce the drug in the course of this year.
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Neither the Subscriber nor AFX News warrants the completeness or accuracy of the Service or the suitability of the Service as a trading aid and neither accepts any liability for losses howsoever incurred. The content on this site, including news, quotes, data and other information, is provided by AFX News and its third party content providers for your personal information only, and neither AFX News nor its third party content providers shall be liable for any errors, inaccuracies or delays in content, or for any actions taken in reliance thereon.
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Posted by j0hn on August 15th, 2007 — in Soma Top News
When Donna McDermott took her seat at Trevor Nelson’s trial last March, she hated him.
Eighteen months earlier, Nelson had killed her husband, Scott, after blowing through a stop sign at almost 90 mph while drunk and on muscle relaxants.
McDermott herself had spent more than two weeks in a coma as a result of the crash, suffering from brain and spinal injuries, 17 fractured ribs, a broken pelvis, a punctured lung, a lacerated liver, a fractured collarbone and a mangled right arm.
On Monday, a Pima County Superior Court hearing officer awarded McDermott and her family $8.5 million for her injuries and the death of her husband.
Through the course of the trial, McDermott, 53, came to a realization.
“I saw that he was just a kid,” McDermott said.
In fact, McDermott suddenly realized that, at the time Nelson “turned her world upside down,” he was 19 — the same age as her daughter, Sara.
Witnesses testified Nelson had been at a party earlier that night and left with some friends in a new Ford Mustang.
McDermott believes Nelson felt compelled by peer pressure that night to drink and to show off his fast, new muscle car.
That being the case, McDermott decided to send a message.
She filed a civil lawsuit against Nelson and the handful of people who supplied him with liquor that night.
Most of the parties settled quickly, with their homeowners insurance paying nearly $2 million to the McDermott family.
Hearing officer Lori Jones issued a default judgment against Nelson, who never responded to the lawsuit. She ordered Nelson to pay Donna $4.5 million for Scott’s loss and her injuries, $3 million to their children, Sara and Kyle, and $1 million to Scott’s parents, Leo and Caroline.
Given the size of the settlement, and the fact Nelson had no car insurance and is in prison, McDermott and her attorney, Elliot Glicksman, acknowledge that the judgment largely is a symbolic one.
Still, they hope it opens some eyes.
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“Parents need to talk to their kids. They have to have an open relationship with them and talk to them about drinking and driving,” McDermott said. “I think a lot of parents are in denial and think their kids would never do something like this.”
Her husband always lectured Sara, McDermott said.
“Scott would always tell Sara: ‘I don’t care what time of the night it is; just call me. I’ll come pick you up, and I won’t give you a hard time.’ ”
The McDermotts were on their way home from renting movies when the collision occurred.
Prosecutors told jurors that Nelson drank a liqueur called Jagermeister at the party, played a game of “beer pong,” took two muscle-relaxant pills and then got into his car.
Nelson went through a stop sign at East Glenn Street and North Mountain Avenue and crashed into the McDermotts’ Mazda sedan.
Donna McDermott, who once took international reservations for American Airlines, is permanently disabled. She can no longer use her right arm to brush her hair, let alone use a computer keyboard.
She also suffers from short-term memory loss and depression.
Court documents indicate Nelson was driving between 78 and 91 mph in a 30 mph zone.
Blood tests showed Nelson had a blood-alcohol level of 0.147, plus Soma, a muscle relaxant, in his system.
The DUI level in Arizona is 0.08 percent.
Nelson, who was charged with second-degree murder, was convicted of manslaughter and sentenced to 8 1/2 years in prison and two years’ probation. He was also ordered to pay $353,219 in restitution.
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Posted by j0hn on August 10th, 2007 — in Soma Top News
AMSTERDAM (Thomson Financial) - Akzo Nobel NV’s Organon said its neuromuscular blocking agent Eslax, a muscle relaxant, has been given approval for use in Japan by local regulatory authorities.
The company said the approval adds to the drug’s list of approved countries, including the United States, Canada and various European countries.
Organon said its Japanese affiliate, Nippon Organon, will introduce the drug in the course of this year.
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The copying, republication or redistribution of AFX News Content, including by framing or similar means, is expressly prohibited without the prior written consent of AFX News.
Neither the Subscriber nor AFX News warrants the completeness or accuracy of the Service or the suitability of the Service as a trading aid and neither accepts any liability for losses howsoever incurred. The content on this site, including news, quotes, data and other information, is provided by AFX News and its third party content providers for your personal information only, and neither AFX News nor its third party content providers shall be liable for any errors, inaccuracies or delays in content, or for any actions taken in reliance thereon.
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Posted by j0hn on July 29th, 2007 — in Soma Top News
No suicide note was found from the spot. A syringe and a vial of the relaxant lay beside the bed on which Dr Kumar’s died, with his trousers, shirt and shoes still on.
Police are at a loss over what led the neurosurgeon to commit suicide. An officer said: “Dr Kushwaha lived with his doctor wife, Kamna, at AIIMS. He was last seen on Thursday night at 9 pm at the institute. His body was discovered on a divan in his brother’s house in Sector 34, about 8 am on Friday, by close relatives who came searching for him.”
The house usually remains locked as Dr Kushwaha’s brother does not live there. He is posted in Aligarh with an oil company.
The police added that Dr Kushawha seemed to have killed himself as soon as he arrived at the Noida house. “His relatives told us that he had been depressed for some time. However, none of them revealed the reason for the depression.
There is nothing in the autopsy report to indicate that there was foul play. His viscera has been sent for forensic analysis,”the officer said.
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Dr Kushwaha’s parents live in Ghazipur, eastern UP, where his father is a farmer. The doctor was the youngest of five children, with two brothers and two sisters. One of his brothers is a farmer.
His sister-in-law Savita Kushwaha, who rushed to Noida from Aligarh after learning of the incident, said: “We cannot think of any reason at all why he should have killed himself.'’
Unable to control her tears, she added: “He was a brilliant doctor and a very well-liked person. He got married three years ago. He had a great future ahead of him. So, we can not imagine why he did this.”
She has phoned Dr Kushwaha’s parents in Ghazipur but told them that he was involved in an accident and was in the intensive care unit of a hospital, “because they wouldn’t be able to take the shock.”
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Posted by j0hn on July 25th, 2007 — in Soma Top News
THE decision of the General Medical Council (GMC) that Dr Michael Munro was not guilty of professional misconduct has, predictably, provoked different responses.
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It will be remembered that in an act which the GMC itself categorised as “tantamount to euthanasia”, Dr Munro injected 23 times the standard dose of a muscle-relaxant drug into two…
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Posted by j0hn on July 22nd, 2007 — in Soma Top News
AMSTERDAM (Thomson Financial) - Akzo Nobel NV (nasdaq: AKZOY - news - people )’s pharmaceutical unit Organon’s application for Marketing Authorization for its sugammadex product has been accepted for review by the European Medicanes Evaluation Agency (EMEA), the company said in a press release.
The Marketing Authorization Application is based on safety and efficacy data collected from over 1700 patients in ten global Phase 3 trials, the results of which were presented at the Euroanaesthesia 2007 congress in Munich last month, the company said.
Organon added that anticipated submissions for the US and Japan are proceeding in line with previously disclosed timelines.
The company said the drug, a selective relaxant binding agent (SRBA) is designed to reverse the effects of the muscle relaxant rocuronium bromide, used as part of general anaesthesia during surgical procedures under the brand names Esmeron and Semuron.
The drug encapsulates the muscle relaxant and renders it inactive.
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The copying, republication or redistribution of AFX News Content, including by framing or similar means, is expressly prohibited without the prior written consent of AFX News.
Neither the Subscriber nor AFX News warrants the completeness or accuracy of the Service or the suitability of the Service as a trading aid and neither accepts any liability for losses howsoever incurred. The content on this site, including news, quotes, data and other information, is provided by AFX News and its third party content providers for your personal information only, and neither AFX News nor its third party content providers shall be liable for any errors, inaccuracies or delays in content, or for any actions taken in reliance thereon.
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Posted by j0hn on July 17th, 2007 — in Soma Top News
The 24-year-old son of former US Vice President and Live Earth pioneer Al Gore has been arrested for possessing drugs.
Police stopped Al Gore III after he was spotted speeding in his suitably eco-friendly Toyota Prius in LA in the early hours of the morning.
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He was arrested after the officer smelled cannabis in the car. Prescription drugs were also found.
The sheriff’s department said: “They found some additional marijuana. They found some Vicadin, Valium, Xanax, Adderol, Soma which is a muscle relaxant.
“Mr Gore was placed under arrest. He did not have a prescription for any of those narcotics.
“He did admit to smoking marijuana early this morning but not enough to influence his driving.”
Mr Gore has now been bailed and a court date will be set within 30 days.
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Posted by j0hn on July 15th, 2007 — in Soma Top News
Ahospital consultant who helped to hasten the deaths of two dying premature babies was cleared of misconduct by the General Medical Council yesterday.
Michael Munro, 41, a consultant neonatologist at Aberdeen maternity hospital, injected a large dose of a muscle relaxant into the babies moments before their deaths in 2005 to ease their distress.
In an act which the GMC said was tantamount to euthanasia, he injected 23 times the recommended dose of pancuronium. However, a disciplinary panel in Manchester found his fitness to practise was not impaired by his actions. The hearing was told that both infants, Baby X and Baby Y, suffered violent spasms in the final throes of death and both appeared to be very distressed. The condition, known as agonal gasping, often occurs when treatment has been withdrawn from the terminally ill.
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The babies’ parents knew what he was doing and that the injection would relieve their suffering and hasten their deaths.
Dr Munro administered a huge 2,000mg dose of the muscle relaxant, which stopped the babies breathing, and they died a short time later. The fitness to practise panel decided the doctor had administered the drug to relieve the children’s suffering rather than hasten their death, although this had been an expected consequence.
The panel rejected claims that his actions were inappropriate and fell below standard, as there were no specific professional guidelines.
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After the hearing, Dr Munro said: “I very much regret any distress that has been caused to the parents by these proceedings. I hope that today’s decision will promote further consideration of the treatment of neonates and end of life decision-making and that this, in turn, will lead to clearer professional guidance.”
Roelf Dijkhuizen, medical director at NHS Grampian, said: “The treatment was not part of accepted practice and therefore, following a thorough investigation, the decision was taken to refer Dr Munro to the GMC. We note the findings of the panel and agree with their view that Dr Munro’s actions were taken with the best interests of the babies in mind.”
Dr Dijkhuizen said that following the incidents, a protocol for all end of life decisions had been put in place to comply with guidelines. He believed the measures would avoid similar incidents in future.
The chair, Jacqueline Mitton, said the panel accepted that Dr Munro had administered pancuronium believing that the babies’ distress could not be relieved by morphine. “Having regard to the lack of clear, specific professional guidance and that it is undisputed that your intention was to relieve suffering rather than to hasten death, the panel is satisfied that at all times you sought to act in the best interests of each baby.”
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Posted by j0hn on July 9th, 2007 — in Soma Top News
A doctor who administered a dose of a paralysing drug to two terminally ill babies said he acted because they were suffering violent body spasms that were “horrendous to witness” for their parents.
Consultant neo-natologist Michael Munro, 41, denied misconduct at a General Medical Council (GMC) fitness to practise panel. He had injected the infants, known only as babies X and Y, with muscle relaxant pancuronium when they suffered the spasms in the moments before their deaths - a phenomenon, known as agonal gasping.
Dr Munro was working at Aberdeen maternity hospital in 2005 when the babies were admitted. He told the hearing that the parents of baby Y were “utterly, utterly distraught”.
He said: “If you put yourself in their shoes, they have already said their last goodbyes to their baby, then suddenly there are these massive, racking agonal gasps which appeared to build up.
“The parents were in tears saying things like ‘I can’t take any more’. I took the decision then to administer pancuronium.”
He said he chose the drug after reading an article in a medical journal. pancuronium appeared ethical and acceptable to be used in this situation.
“I explained to the parents that this drug was to be used to ease the suffering but that one of the consequences of its use may be to hasten death,” he told the hearing. “They were happy with that.”
In the case of baby X, Dr Munro was called to certify death. He discovered a faint heartbeat and the child began agonal gasping.
Dr Munro said: “I tried to explain [to the parents] that this was simply a reflex although I felt in my heart that this baby was distressed.”
Following a discussion with the child’s family, Dr Munro made the decision to administer a dose of pancuronium and the infant died a short while later.
In both cases, he failed to record the drug’s use in the medical notes, but denied he had attempted to hide his actions, conceding that his note-taking had been inadequate.
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Following an application by Dr Munro’s lawyer, Michael Mylonas, a number of the charges against the doctor were dropped this morning.
Andrew Long, representing the GMC, said that none of the children’s parents were unhappy with the doctor’s treatment of their babies
The hearing, in Manchester, was told baby Y was born on June 20, 2005 two weeks premature and baby X was born on December 5, 2005, more than three months early.
Both children suffered complications during pregnancy with baby X having a serious brain haemorrhage, while baby Y was born with pulmonary hypoplasia and pulmonary hypertension.
Giving evidence at the beginning of his defence, Dr Munro described the final moments in the life of baby Y.
He said the decision was taken for treatment to be withdrawn and the infant was given to his parents to hold. The youngster’s breathing faded and a nurse and the parents believed the child had died.
Dr Munro returned to the baby to certify death and found its heart was beating faintly. He said: “Baby started agonal gasping. Baby then started to build on this agonal gasping - that is to say it increased in frequency.
“I felt the baby looked distressed because the baby’s whole body was being wracked by these movements. There was movement of the limbs and chest movement. I couldn’t see how this could not be distressing.”
The hearing began last Thursday and is continuing.
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